NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)

NT-proBNP: a Useful Tool for the Detection of Acute Pulmonary Artery Embolism in Post-surgical Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01633671

Enrollment

Registered

2012-07-04

Start date

2008-11-30

Completion date

2011-12-31

Last updated

2012-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Embolism, Pulmonary Embolism Without Mention of Acute Cor Pulmonale

Keywords

Misadventures to Patients During Surgical and Medical Care, Pulmonary Embolism Without Acute Cor Pulmonale, Pulmonary Embolism Without Mention of Acute Cor Pulmonale

Brief summary

In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital protocol. To definitively confirm or exclude APE, all patients underwent an angiographic CT-scan of the thorax.

Detailed description

In patients with suspected APE referred to the intensive care unit after major surgery, serum NT-proBNP, Troponin-I and D-dimers were measured according to the standard hospital protocol. Blood samples were obtained within one hour after the onset of clinical symptoms. Definitive confirmation or exclusion of APE was performed with an angiographic CT-scan of the thorax.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

all patients referred to the ICU with suspected APE

Exclusion criteria

none

Design outcomes

Primary

Measure	Time frame
Acute pulmonary embolism: CT-proof yes vs. no	1 hour after onset of clinical symptoms

Countries

Germany

Outcome results