Nutrition Assessment
Conditions
Keywords
Sodium, Potassium, Iodine, Creatinine
Brief summary
This proposed calibration study is designed to evaluate the correlation of urinary sodium excretion between NHANES timed urine and 24-hour urine collections.
Detailed description
The study will be conducted with 400 volunteer participants aged 18-39 years old. Participants will be asked to collect urine samples over a 24-hour period. One-third of the participants (n=133) will be asked to collect a second 24-hour urine 4-11 days later. A 24-hour dietary recall interview will be collected after the completion of each 24-hour urine collection. Results from this study will be used to assess how well the sodium excretion estimated from NHANES timed urine correlates with data from 24-hour urine collection. It will provide valuable information on the potential of NHANES timed urine collections to be used to characterize trends in U.S. population sodium intake.
Interventions
None listed
Sponsors
National Institutes of Health (NIH)
Centers for Disease Control and Prevention
Study design
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 39 Years
Healthy volunteers
Yes
Inclusion criteria
English speaking * Aged 18-39 years old * 50% Black; 50% all other * 50% male; 50% female * At least 50 (25 male; 25 female) of the 400 participants likely to have high sodium diet indicated by selected dietary behaviors * At least 50 (25 male; 25 female) of the 400 participants likely to have low sodium diet indicated by selected dietary behaviors
Exclusion criteria
* Pregnant or trying to get pregnant. * Taking loop diuretics * Chronic kidney disease * New hypertension treatment or change in hypertension treatment in the last 2 weeks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Usual sodium intake | one day | Usual sodium intake based on 24-hour sodium excretions (two measurements for a one-third subset 4-11 days after the first collection) using measurement error models |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Usual potassium intake | one day | Usual potassium intake based on 24-hour potassium excretions (two measurements for a one-third subset) using measurement error models |
| Creatinine excretion | one day | Based on 24-hour creatinine excretion |
| Usual iodine intake | one day | Usual sodium intake based on 24-hour sodium excretions (two measurements for a one-third subset 4-11 days after the first collection) using measurement error models |
Outcome results
None listed