MR-Guided Laser Ablation of Hepatic Tumors

Technical Success, Safety, and Short-term Efficacy for MR-Guided Laser Ablation of Hepatic Tumors

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01630239

Enrollment

Registered

2012-06-28

Start date

2012-06-30

Completion date

2015-03-31

Last updated

2015-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft Tissue Tumors

Brief summary

This is a pilot study to investigate the performance of MR-guided Laser Induced Thermal Therapy (LITT) in the treatment of liver tumors.

Interventions

PROCEDURELaser ablation

Laser ablation of hepatic tumors

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with soft tissue tumor metastases to the liver who are referred to Interventional Radiology for treatment. * Surgery is not a viable or desirable alternative therapy at the time of enrollment * Radiation therapy has failed or not indicated or can be safely postponed * Tumor size ≤ 5 cm at its largest diameter * Tumor position is not in the central liver hilum * Performance status is ECOG 2 or better in adults * Patient is able to undergo MRI

Exclusion criteria

* Patients with pacemaker or defibrillator * Patients with metallic surgical clips close to the site of the intended ablation * Pregnant women * Patients with hilar liver lesions

Design outcomes

Primary

Measure	Time frame
MR Images	6 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026