Executive Functioning and Mindfulness in Adults With Attention Deficit/Hyperactivity Disorder Imaging

Executive Functioning and Mindfulness in Adults With ADHD Imaging

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01629914

Acronym

EFMImaging

Enrollment

Registered

2012-06-28

Start date

2012-06-30

Completion date

2013-01-31

Last updated

2017-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention-deficit/Hyperactivity Disorder

Keywords

Attention-deficit/hyperactivity disorder, executive functioning, mindfulness meditation, magnetic resonance imaging, healthy

Brief summary

The main purpose of this study is to evaluate changes in brain functioning using an MRI machine following mindfulness meditation training.

Detailed description

The broad objective of this proposal is to identify functional neuroanatomical correlates of changes in executive brain functioning prior to and following an 8-week, group-based mindfulness meditation intervention within a group of 10 adults diagnosed with Attention-deficit/hyperactivity disorder (ADHD). Another group of 10 adults diagnosed with ADHD will be placed in the waitlist condition. Our primary hypothesis is that adults with ADHD in the treatment group will exhibit improved performance on a series of executive functioning tasks and that exposure to task stimuli will correspond to changes in neural functioning following an 8-week, group-based mindfulness intervention. Brain responses will be measured using blood-oxygenation-level-dependent (BOLD) fMRI signal in brain regions associated with emotional and executive processes prior to and following treatment.

Interventions

BEHAVIORALMindfulness Meditation

8-week, group-based mindfulness meditation intervention

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* ages 18-50 years * meet DSM-IV criteria for ADHD * intellectual functioning ≥ 80 as assessed by an IQ screener * generally healthy (i.e., no major medical problems)

Exclusion criteria

* major medical condition that would make participation unsafe (e.g., have pacemaker or other metallic implant), uncomfortable (e.g., chronic pain) * claustrophobic, or abnormally afraid of closed-in places * current drug use

Design outcomes

Primary

Measure	Time frame	Description
change from baseline in blood-oxygenation-level-dependent (BOLD) fMRI signal	baseline and 8-weeks	Participants will be scanned prior to and following an 8-week group-based mindfulness meditation intervention

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026