Cutaneous Lupus Erythematosus
Conditions
Brief summary
Studies have shown that there are significant differences in severity and outcome of lupus in patients of colored skin compared with Caucasians. There are many factors that lead to this discrepancy: genetics, poverty, education level, as well as behavioral and cultural factors. Cutaneous Lupus Erythematosus (CLE) is a disease of flares and remissions with identifiable triggers. One of the most aggravating triggers in CLE is sun exposure. The investigators hypothesize that there are disparities in knowledge about photoprotection, leading to poorer outcomes in minority ethnic groups. This study aims to assess knowledge of risk factors and triggers, especially sun exposure, and the effects on quality of life of Caucasian and minority populations, by conducting an assessment survey and subsequent teaching intervention on appropriate skin protection techniques including appropriate sun screen application, and use of sun-protective clothing. After three months a survey to evaluate knowledge retention about and the application of the educational intervention will be conducted.
Interventions
BEHAVIORALCutaneous Lupus educational script
Subjects will listen to a short informational script on Cutaneous lupus and skin protection
Sponsors
Northwestern University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Subjects with a diagnosis of cutaneous lupus erythematous * Subjects ages 18 years of age and older and able to give consent
Exclusion criteria
* That which does not fit the inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | immediately before and after an educational lecture | In order to evaluate the immediate effect of an educational lecture about cutaneous lupus erythematosus (CLE) and sun protection, subjects completed a written questionnaire to assess knowledge about CLE and sun protection immediately before and after the educational lecture. The percentage of subjects who correctly answered a knowledge assessment item were calculated pre- and post-educational lecture. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | before and 3 months after an educational lecture | In order to evaluate the long-term effect of an educational lecture about cutaneous lupus erythematosus (CLE) and sun protection, subjects completed a questionnaire to assess knowledge about CLE and sun protection behaviors immediately before and three months after an educational lecture. The percentage of subjects who correctly answered a knowledge or behavioral assessment item were calculated pre- and three months post-educational lecture. |
Countries
United States
Participant flow
Recruitment details
Adult subjects with cutaneous lupus erythematosus (CLE) were recruited from Northwestern University's dermatology and rheumatology clinics.
Participants by arm
| Arm | Count |
|---|---|
| Cutaneous Lupus Erythematosus (CLE) Subjects completed a written questionnaire to collect demographic data, including personal history of CLE and sun protection behaviors, and to assess knowledge about CLE and sun protection. Next, subjects listened to a scripted, educational lecture about CLE and sun protection, and then immediately completed a post-lecture written questionnaire to assess knowledge about CLE and sun protection. Three months after the educational lecture, subjects were contacted by phone to complete a final knowledge and behavioral assessment. | 31 |
| Total | 31 |
Baseline characteristics
| Characteristic | Cutaneous Lupus Erythematosus (CLE) |
|---|---|
| Age, Categorical <=18 years | 0 Participants |
| Age, Categorical >=65 years | 3 Participants |
| Age, Categorical Between 18 and 65 years | 28 Participants |
| Region of Enrollment United States | 31 participants |
| Sex: Female, Male Female | 26 Participants |
| Sex: Female, Male Male | 5 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 31 |
| serious Total, serious adverse events | 0 / 31 |
Outcome results
Primary
Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture
In order to evaluate the immediate effect of an educational lecture about cutaneous lupus erythematosus (CLE) and sun protection, subjects completed a written questionnaire to assess knowledge about CLE and sun protection immediately before and after the educational lecture. The percentage of subjects who correctly answered a knowledge assessment item were calculated pre- and post-educational lecture.
Time frame: immediately before and after an educational lecture
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Sun exposure linked to lupus | 81 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Exposure to UV rays with indoor tanning | 39 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should use sun-protective clothing to protect skin | 94 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should apply sunscreen under makeup | 68 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should avoid sun during hours of 10 am - 2 pm | 84 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Smoking linked to lupus | 19 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Risk of lupus for people of color | 52 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should apply sunscreen before going outdoors | 97 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Type of sunscreen that should be used | 87 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Time to apply sunscreen before sun exposure | 39 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Sun brings out lupus lesions | 74 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Exposure to UV rays while indoors through glass | 68 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should apply sunscreen under makeup | 100 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Smoking linked to lupus | 90 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Sun exposure linked to lupus | 97 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Sun brings out lupus lesions | 97 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should use sun-protective clothing to protect skin | 100 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Type of sunscreen that should be used | 90 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Exposure to UV rays while indoors through glass | 100 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Exposure to UV rays with indoor tanning | 100 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should avoid sun during hours of 10 am - 2 pm | 100 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Should apply sunscreen before going outdoors | 100 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Time to apply sunscreen before sun exposure | 48 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge Assessment Item Immediately Before and After an Educational Lecture | Risk of lupus for people of color | 94 percentage of participants |
Secondary
Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture
In order to evaluate the long-term effect of an educational lecture about cutaneous lupus erythematosus (CLE) and sun protection, subjects completed a questionnaire to assess knowledge about CLE and sun protection behaviors immediately before and three months after an educational lecture. The percentage of subjects who correctly answered a knowledge or behavioral assessment item were calculated pre- and three months post-educational lecture.
Time frame: before and 3 months after an educational lecture
| Arm | Measure | Group | Value (NUMBER) |
|---|---|---|---|
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Smoking linked to lupus | 19 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Sun exposure linked to lupus | 81 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Sun brings out lupus lesions | 74 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply correct type of sunscreen | 58 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Reapply sunscreen at correct time if dry | 19 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Reapply sunscreen at correct time if wet | 23 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Avoid more than two hours of sun exposure | 25 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Avoid sun exposure between 10 am - 2 pm | 71 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Should use sun-protective clothing to protect skin | 94 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Seek medical care for change in rash appearance | 97 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply sunscreen before going outdoors | 71 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply sunscreen at correct time prior to exposure | 32 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Limit outdoor social gatherings | 55 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Wear sun-protective clothing | 68 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Avoid indoor tanning | 94 percentage of participants |
| Pre-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply sunscreen under makeup | 45 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Avoid sun exposure between 10 am - 2 pm | 71 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Smoking linked to lupus | 45 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply sunscreen at correct time prior to exposure | 45 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Sun exposure linked to lupus | 77 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Should use sun-protective clothing to protect skin | 71 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Sun brings out lupus lesions | 77 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Avoid indoor tanning | 81 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply correct type of sunscreen | 58 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Seek medical care for change in rash appearance | 81 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Reapply sunscreen at correct time if dry | 13 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Limit outdoor social gatherings | 48 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Reapply sunscreen at correct time if wet | 19 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply sunscreen before going outdoors | 71 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Avoid more than two hours of sun exposure | 26 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Apply sunscreen under makeup | 52 percentage of participants |
| Post-educational Lecture | Percentage of Subjects Who Correctly Answered a Knowledge or Behavioral Assessment Item Before and 3 Months After an Educational Lecture | Wear sun-protective clothing | 81 percentage of participants |