Medical Data Collection of Patients With Head and Neck Cancer Treated With Proton Therapy

Prospective Data Collection of Patients Treated With Proton Therapy for Head and Neck Malignancies

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01627093

Enrollment

450

Registered

2012-06-25

Start date

2012-01-06

Completion date

2032-04-30

Last updated

2026-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Carcinoma

Brief summary

This trial collects medical information from patients with head and neck cancer that have received or are scheduled to receive proton therapy. Collecting and analyzing medical information from patients may provide information on the outcomes and treatment related side effects of proton therapy for head and neck cancer and help doctors improve therapy for future patients with head and neck cancer.

Detailed description

PRIMARY OBJECTIVE: I. To evaluate the outcomes in patients who have received treatment for their head and neck malignancy with proton radiation therapy. OUTLINE: Patients complete questionnaires over 30 minutes before treatment begins, at each visit during treatment, and again at all follow-up visits related to treatment. Patients also have their medical records reviewed.

Interventions

OTHERMedical Chart Review

Review of medical records

OTHERQuestionnaire Administration

Complete questionnaires

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients documented to have head and neck cancer treated with proton therapy at MDACC from January 1, 2008 through April 30, 2012 and patients who receive treatment from May 1, 2012 through December 31, 2018

Design outcomes

Primary

Measure	Time frame	Description
Overall survival analysis of proton therapy for head and neck malignancies	7 years	Retrospective chart analysis will be performed on all patients documented to have head and neck cancer, treated with Proton Therapy at MDACC from January 1, 2008 through April 30, 2012. Prospective chart analysis will be performed on head and neck cancer patients currently being treated at MD Anderson Cancer Center beginning May 1, 2012 through December 31, 2018. Overall survival estimated using Kaplan-Meier method. Cox proportional hazards regression used to explore predictors of time-to-event outcomes. Mann-Whitney test used to compare continuous parameters between temporal cohorts.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORSteven J Frank

M.D. Anderson Cancer Center

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 22, 2026