Study of Modified Constraint-Induced Aphasia Therapy Schedule to Treat Patients Following Sub-acute Stroke

Constraint-Induced Aphasia Therapy Following Sub-acute Stroke: A Modified Therapy Schedule

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01625676

Acronym

MCIAT

Enrollment

100

Registered

2012-06-21

Start date

2004-08-31

Completion date

2011-12-31

Last updated

2012-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia

Keywords

Aphasia, Rehabilitation of Speech and Language Disorders

Brief summary

The purpose of this study is to assess the feasibility of modified Constraint-Induced Aphasia Therapy (CIAT) in the early sub-acute stage and to examine the efficacy of modified CIAT versus standard treatment with the same intensity of intervention.

Interventions

OTHERInvestigate efficacy of modified ciat schedule

2 hours of training over 15 days

OTHERexamine the efficacy of standard treatment versus modified ciat schedule

2 hours of training over 15 days

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

34 Years to 84 Years

Healthy volunteers

Inclusion criteria

* clinical diagnosis of first-ever stroke * aphasia in sub-acute stage * german speakers

Exclusion criteria

* presence of residual aphasia * dysarthria and apraxia of speech

Design outcomes

Primary

Measure	Time frame
Change of aphasia and aphasic syndromes by Aachen Aphasia Test (AAT)	pretreatment and 4 weeks
change from pretreatment in Aachen Aphasia Test at 8 weeks	pretreatment and 8 weeks
change from pretreatment in Aachen Aphasia Test at 1 year	pretreatment and 1 year

Secondary

Measure	Time frame
Change of Communicative Activity (CAL)	pretreatment and 4 weeks
change from pretreatment in communication activity (CAL)at 8 weeks	pretreatment and 8 weeks
Change from pretreatment in communication activity (CAL)at 1 year	pretreatment and 1 year

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026