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Social Cognition in Longstanding Psychosis

Social Cognition in Longstanding Psychosis

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01624831
Enrollment
9
Registered
2012-06-21
Start date
2011-11-30
Completion date
2015-11-30
Last updated
2020-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar Disorder With Psychotic Features, Major Depression With Psychotic Features, Psychosis Not Otherwise Specified (NOS), Schizoaffective Disorder, Schizophrenia

Keywords

Psychosis, schizophrenia, schizoaffective disorder, Bipolar disorder with psychotic features, Major depression with psychotic features, Psychosis NOS, Social Cognition

Brief summary

In the current study, the investigators propose to measure the five domains of social cognition identified by the National Institute of Mental Health (NIMH) as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

Detailed description

There is growing evidence that individuals with longstanding psychotic disorders suffer from deficits in social cognition (i.e., the cognitive skills needed to successfully navigate social interactions). However, to date, there have been few attempts to measure multiple components of social cognition within the same population of individuals with psychosis. Thus, the interrelationships between various aspects of social cognition remain unclear. In the current study, the investigators propose to measure the five domains of social cognition identified by NIMH as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

Interventions

None listed

Sponsors

University of Arizona
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosis of a schizophrenia spectrum disorder or an affective disorder with psychotic features per the Diagnostic and Statistical Manual of Mental Disorders-IV-Text Revised (DSM-IV-TR) criteria using the Structured Clinical Interview for the DSM-IV. * Duration of psychotic symptoms greater than or equal to 5 years determined using the Symptom Onset in Schizophrenia Inventory * Age 18-75 * No evidence of mental retardation. * Able to provide informed consent as evidenced by passing the informed consent quiz with a score of 80% or greater. * Fluent in English as assessed per self-report from participant

Exclusion criteria

* Unwilling or unable to complete study assessments (e.g., unable to read self-report questionnaires) * Subject is currently pregnant per subject's report

Design outcomes

Primary

MeasureTime frameDescription
Emotion RecognitionBaseline and 6 monthsChange from baseline to 6 month assessment in ability to recognize emotions displayed by others assessed using the Facial Emotion Identification Test
Attribution StyleBaseline and 6 monthsChange from baseline to 6 month assessment in tendency to attribute events that occur to situational, personal, or internal factors assessed using the Internal, Personal, and Situational Attributions Questionnaire
Social PerceptionBaseline and 6 monthsChange from baseline to 6 month assessment in ability to understand concrete and abstract components of everyday social interactions assessed using the Social Cues Recognition Test
Social KnowledgeBaseline and 6 monthsChange from baseline to 6 month assessment in knowledge of goals and actions associated with familiar and unfamiliar social activities assessed using the Situational Features Recognition Test
Theory of MindBaseline and 6 monthsChange from baseline to 6 month assessment in ability to identify the mental states of other individuals assessed using the Hinting Test

Secondary

MeasureTime frameDescription
PsychosisBaseline and 6 monthsChange from baseline to 6 month assessment in severity of positive and negative psychotic symptoms assessed using the Positive and Negative Syndrome Scale
Social FunctioningBaseline and 6 monthsChange from baseline to 6 month assessment in level of social functioning assessed using the Social Functioning Scale
Service UtilizationBaseline and 6 monthsChange from baseline to 6 month assessment in utilization of medical services assessed using the Service Utilization Record Form
Self-Determination Needs SatisfactionBaseline and 6 monthsChange from baseline to 6 month assessment in ability to fulfill basic needs for autonomy, competence, and relatedness assessed using the Basic Psychological Needs Scale
Locus of ControlBaseline and 6 monthsChange from baseline to 6 month assessment in perception of one's ability to control events in the environment assessed using the Multidimensional Locus of Control Scale
Cognitive representation of illnessBaseline and 6 monthsChange from baseline to 6 month assessment in understanding of nature of psychotic illness assessed using the Illness Perception Questionnaire
Emotional AwarenessBaseline and 6 monthsChange from baseline to 6 month assessment in awareness of one's own emotions as well as emotions of others assessed using the Levels of Emotional Awareness Scale
MindfulnessBaseline and 6 monthsChange from baseline to 6 month assessment in awareness and acceptance of feelings and events assessed using the Philadelphia Mindfulness Scale
Self-efficacyBaseline and 6 monthsChange from baseline to 6 month assessment in confidence with regard to control of psychotic symptoms assessed using the Self-Efficacy Scale for Schizophrenia
Neuropsychological functioningBaseline and 6 monthsChange from baseline to 6 month assessment in neuropsychological functioning assessed using the MATRICS Consensus Cognitive Battery
Social SupportBaseline and 6 monthsChange from baseline to 6 month assessment in level of social support assessed using the Measure of Perceived Support
Experience of StigmaBaseline and 6 monthsChange from baseline to 6 month assessment in experience of stigma with regard to mental illness assessed using the Stigma Questionnaire
quality of lifeBaseline and 6 monthsChange from baseline to 6 month assessment in quality of life assessed using the WHO Quality of Life Scale-Brief
stage of recoveryBaseline and 6 monthsChange from baseline to 6 month assessment in stage of recovery with regard to mental illness assessed using the Stages of Recovery Instrument
Coping skillsBaseline and 6 monthsChange from baseline to 6 month assessment in level of coping skills assessed using the Ways of Coping Questionnaire
Time perspectiveBaseline and 6 monthsChange from baseline to 6 month assessment in time orientation assessed using the Zimbardo Time Perspective Instrument
Medication adherenceBaseline and 6 monthsChange from baseline to 6 month assessment in adherence to psychiatric medication assessed using the Medication Adherence Rating Scale
Illness UncertaintyBaseline and 6 monthsChange from baseline to 6 month assessment in uncertainty with regard to cause, course, and treatment of illness assessed using the Mischel Uncertainty in Illness Scale
Relationship with familial caregiversBaseline and 6 monthsChange from baseline to 6 month assessment in relationship with familial caregivers assessed using the Perception of Parents Scale
AnxietyBaseline and 6 monthsChange from baseline to 6 month assessment in anxiety assessed using the Beck Anxiety Inventory
DepressionBaseline and 6 monthsChange from baseline to 6 month assessment in depression assessed using the Beck Depression Inventory

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026