Radial Artery Versus Saphenous Vein Patency (RSVP) Trial - 10 Year Follow-up

Randomised, Controlled Trial Comparing Angiographic Patency of the Radial Artery Versus the Saphenous Vein Used as Free Aorto-coronary Grafts in Coronary Revascularisation (RSVP Trial) - 10-year Follow-up

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01622387

Enrollment

Registered

2012-06-19

Start date

2011-10-13

Completion date

2014-07-03

Last updated

2019-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Coronary artery bypass surgery, Arteries, Veins, Conduits

Brief summary

During coronary bypass surgery, veins are taken from the leg and applied to the heart and aorta to 'bypass' narrowings in the coronary arteries. However using an artery in the chest, the internal mammary artery, means that the bypass lasts longer than using veins. The investigators recently showed that using an artery from the arm as a bypass vessel, the radial artery, also had less furring up than veins 5 years after surgery. Now the investigators would like to ask patients to come back for an angiogram 10 years following surgery.

Interventions

PROCEDURECoronary artery bypass (CABG) surgery using a radial arterial conduit

Use of radial artery as a bypass conduit/graft to the left circumflex coronary artery region of the heart in CABG surgery

PROCEDURECoronary artery bypass surgery using a long saphenous vein conduit

Use of long saphenous vein as a graft/conduit vessel to the left circumflex coronary artery region of the heart in CABG surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Included in the RSVP study * Willing to attend for coronary angiography * Willing to give written informed consent

Exclusion criteria

* Contraindication to coronary angiography * participation in research project within previous 60 days * unwilling to give written informed consent

Design outcomes

Primary

Measure	Time frame	Description
Proportion of radial artery and saphenous vein grafts patent at 10 years	10 years post surgery	Comparison of the patency of radial artery and long saphenous aorto-coronary bypass grafts at 10 years, assessed by an independent observer

Secondary

Measure	Time frame	Description
Angiographic visual grading	10 years post surgery	Compare secondary angiographic visual grading in radial artery and long saphenous vein grafts
Patency (patent or complete occlusion, and secondary visual grading) of radial artery and internal mammary artery coronary bypass grafts	10 years post surgery	Compare the patency (patent or complete occlusion, and secondary visual grading) of radial artery and internal mammary artery coronary bypass grafts

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026