Timing of Intrauterine Insemination (IUI) 24 or 48 Hours After Spontaneous Luteinizing Hormone (LH) Peak

Timing of IUI 24 or 48 Hours After Spontaneous LH Peak: a Randomised Controlled Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01622023

Enrollment

435

Registered

2012-06-18

Start date

2010-10-31

Completion date

2013-06-30

Last updated

2019-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy

Keywords

insemination, donor sperm, natural cycle

Brief summary

The aim of the present study is to prospectively evaluate whether performing an intra-uterine insemination 24 hours after the spontaneous LH peak may result in significantly higher ongoing pregnancy rates compared to 48 hours.

Interventions

PROCEDUREintra-uterine insemination

Artificial insemination is the process by which sperm is placed into the reproductive tract of a female for the purpose of impregnating the female by using means other than sexual intercourse or natural insemination.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 39 Years

Healthy volunteers

Inclusion criteria

* below 39 years of age on the day of LH peak * donor semen * natural cycle (without CC) * cycle with less than 3 follicles reaching 15 mm of diameter or more. * with basal hormonal values of progesterone ( \< 1,2 ng/dl)

Exclusion criteria

The patients excluded are women * who underwent more than 6 intrauterine inseminations, * with tubal infertility

Design outcomes

Primary

Measure	Time frame
pregnancy rate	end of 2013 (up to 2 years)

Secondary

Measure	Time frame
live birth rate	end of 2013 (up to 2 years)

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026