Development of a Clinical Prediction Rulefor Neck Manipulation

Development of a Clinical Prediction Rule to Identify Patients With Neck Pain Likely to Benefit From Cervical Spine Manipulation and Exercise

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01620905

Enrollment

Registered

2012-06-15

Start date

2008-11-30

Completion date

2011-06-30

Last updated

2016-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical Neck Pain

Brief summary

Cervical spine manipulation has been shown to be helpful for some patients with neck pain. This study sought to determine factors which were predictive of which patients with neck pain would benefit from manipulation.

Interventions

PROCEDUREManipulation

Single level cervical spine joint manipulation

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* age 18 to 60 years * primary report of neck pain with or without unilateral upper extremity symptoms * baseline neck disability index score of 10 points (out of 50) or greater

Exclusion criteria

* any medical red flags suggesting that the etiology of symptoms might be nonmusculoskeletal * diagnosis of cervical spinal stenosis (as identified in the patients' medical intake form) * bilateral upper extremity symptoms * evidence of central nervous system involvement * history of whiplash injury within 6 weeks of the examination * pending legal action regarding their neck pain * 2 or more positive neurologic signs consistent with nerve root compression (changes in sensation, myotomal weakness, or decreased deep tendon reflexes) * any history of cervical spine surgery, rheumatoid arthritis, osteoporosis, osteopenia, or ankylosing spondylitis.

Design outcomes

Primary

Measure	Time frame	Description
Global Rating of Change Scale	48 hours post intervention	15 point likert scale rating perceived recovery

Secondary

Measure	Time frame	Description
Neck Disability Index	48 hours and 96 hours post intervention	10 item questionnaire measuring perceived disability (range 0 to 50)
Numeric Pain Rating Scale	48 hours and 96 hours post intervention	Average pain scores (0 - no pain to 10 - worst imaginable pain) taken for current rating, best in last 24 hours and worst in last 24 hours

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026