Acute Heart Failure, COPD Exacerbation
Conditions
Keywords
COPD, Left Ventricular Failure, Valsalva Manoeuver
Brief summary
Left ventricular failure (LVF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis . The investigators expect that Valsalva Maneuver (VM) could be useful in this issue.
Interventions
OTHERValsalva maneuver
Sponsors
University of Monastir
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* We included in this group, patients with a history (previous history) of COPD who consulted the emergency room for an exacerbation of COPD defined by a respiratory rate\> 25c/min and a pH \<7.35 and a PaCO2 \>6 KPa. * This group is also divided into two groups according to clinical expert assessment and the BNP value: Group1 : BNP\> 400pg/ml, Group2 : BNP \<400PG / ml
Exclusion criteria
* We excluded from this study patients with Prominent cardiac arrest * Rhythm disorders including severe tachycardia arrhythmia * Auricular fibrillation * Hemodynamic instability requiring the use of vasoactive drugs and a contre indications of non invasive ventilation such us consciousness disorders with a Glasgow score \<12/15,a swallowing disorder * A significant bronchial obstruction ,the upper airway obstruction , in upper gastrointestinal bleeding in progress, an extreme obesity and Cirrhosis or cancer. * We are also excluded patients who did not cooperate and those who refused the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| left ventricular dysfunction | 24 hours |
Countries
Tunisia
Outcome results
None listed