Role of New Diagnostic Tool in Device (ICD / PM) Associated Infections

Device Associated Infections - Role of New Diagnostic Tools

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01619267

Acronym

DIRT

Enrollment

103

Registered

2012-06-14

Start date

2012-01-31

Completion date

2013-04-30

Last updated

2017-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biomarkers in Device Associated Infections

Keywords

pacemaker defibrillator infection

Brief summary

Infections related to implantable pacemakers or cardioverters defibrillators are sometimes difficult to be diagnosed. Diificulties in the diagnosis include a low sensitivity of standard markers of inflammation such as C-reactive protein or white blood cell count and the diagnosis is mainly based on the clinical presentation. The observational DIRT-study evaluates if new biomarkers may be more suitable to support a diagnosis of device associated infections than the currently available ones.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* device associated infections

Exclusion criteria

* malignancy * cytostatic or immunomodulating therapy

Design outcomes

Primary

Measure	Time frame	Description
procalcitonine	no follow-up	procalcitonine is determined at inclusion and correlated to infectíon status

Countries

Croatia, Germany, Italy

Outcome results