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Cortical Organization in Allogeneic Transplants or Heterotopic Hand Replants

Cortical Organization in Allogeneic Transplants or Heterotopic Hand Replants

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01618682
Enrollment
60
Registered
2012-06-13
Start date
2012-03-31
Completion date
2019-03-31
Last updated
2018-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hand Replant, Hand Transplant

Keywords

hand transplant, hand replant

Brief summary

The investigators hope to gain insights into the functional organization of the human cerebral cortex in response to upper limb amputation and surgical interventions including hand replantation and hand transplantation.

Interventions

None listed

Sponsors

University of Missouri-Columbia
CollaboratorOTHER
Christine M. Kleinert Institute for Hand and Microsurgery
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* between 18-70 yrs old * undergone successful allogeneic transplantation of one or both hands OR undergone successful reattachment of one or both hands OR will have experienced surgical repair of one or more severed nerves (ulnar, medial, radial, digital in the upper limb * must speak English

Exclusion criteria

* younger than 18 years or older than 70 years * not undergone a replant or transplant

Design outcomes

Primary

MeasureTime frameDescription
Ultrasound BiomicroscopyUp to 12 monthsWe will scan the cross section of the medial nerve at the pisiform bone level to determine the level of CTS with Ultrasound Biomicroscopy machine. This device is not approved for clinical decisions, only used for research purposes.

Secondary

MeasureTime frameDescription
Grip StrengthUp to 12 months
Pinch StrengthUp to 12 months
DASH QuestionnaireUp to 12 monthsSubjects will complete the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire.

Countries

United States

Contacts

Primary ContactChristina L Kaufman, PhD
ckaufman@cmki.org502-562-0390
Backup ContactDonna Stacy, RN, MSN
dstacy@cmki.org502-562-0313

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026