Neoplasms
Conditions
Keywords
neoplasms, adolescent, young adult, medication adherence
Brief summary
To explore use of a smart-phone medication reminder application to promote adherence to oral medications by AYA with cancer.
Detailed description
Non-adherence to oral medications is a prevalent problem in adolescents and young adults (AYA) with cancer that may impact both survival and quality of life while on treatment. The purpose of this study is to explore use of a smart-phone medication reminder application to promote adherence to oral medications by AYA with cancer. The study's primary aim is to explore the feasibility and acceptability of using a smart-phone medication reminder application to promote adherence to oral medications by AYA with cancer as well as to characterize application use. Secondary aims include: 1) to obtain initial estimates of intervention effect- measured by pre-intervention to post-intervention differences in perceived behavioral control for adherence, intention to adhere, and adherence behavior - to inform design of a future trial powered to detect a clinically significant effect of smart-phone medication reminder application use on adherence to oral medications; and 2) to examine the relationships among perceived behavioral control for adherence, intention to adhere, and adherence behavior. A pre-post single group design will be used. Data will be collected weekly for 4 weeks before introduction of the intervention and for 8 weeks following introduction of the intervention. Analytic approaches will include descriptive statistics and generalized estimating equation (GEE) modeling.
Interventions
None listed
Sponsors
Oncology Nursing Society
University of Utah
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 29 Years
Healthy volunteers
No
Inclusion criteria
1)15-29 year olds receiving treatment for any type of cancer, either primary or recurrent/relapsed disease. 2\) Patient has completed at least one month of therapy 3)Patient is expected to remain on therapy for 3 month duration of study 4\) Patient has an iPhone, iPad, or iTouch running iOS 4.0 or later 5\) Patient is willing to use a smart-phone medication reminder application-
Exclusion criteria
1)Patients who are unable to speak/read/write English as required for use of smart-phone medication reminder application and completion of study measures.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility and Acceptability of Using a Smart-phone Medication Reminder Application to Promote Adherence to Oral Medications by AYA With Cancer. | ongoing study weeks 5-12 | Feasibility was assessed through participants' application usage and responses to self-reported questions about their use of the application. Acceptability was assessed through participants' perceived ease of use and perceived usefulness of the application. |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Participants All participants | 32 |
| Total | 32 |
Baseline characteristics
| Characteristic | Participants |
|---|---|
| Age, Categorical <=18 years | 17 Participants |
| Age, Categorical >=65 years | 0 Participants |
| Age, Categorical Between 18 and 65 years | 15 Participants |
| Region of Enrollment United States | 32 participants |
| Sex: Female, Male Female | 12 Participants |
| Sex: Female, Male Male | 20 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 32 |
| serious Total, serious adverse events | 0 / 32 |
Outcome results
Primary
Feasibility and Acceptability of Using a Smart-phone Medication Reminder Application to Promote Adherence to Oral Medications by AYA With Cancer.
Feasibility was assessed through participants' application usage and responses to self-reported questions about their use of the application. Acceptability was assessed through participants' perceived ease of use and perceived usefulness of the application.
Time frame: ongoing study weeks 5-12
| Arm | Measure | Group | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|---|
| Participants | Feasibility and Acceptability of Using a Smart-phone Medication Reminder Application to Promote Adherence to Oral Medications by AYA With Cancer. | Used application at least once | 21 Participants |
| Participants | Feasibility and Acceptability of Using a Smart-phone Medication Reminder Application to Promote Adherence to Oral Medications by AYA With Cancer. | Took medication immediately upon getting reminder | 13 Participants |