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Evaluation of Sodium Hypochlorite as a Denture Cleanser

Denture Condition: Influence on Masticatory Performance, Volatile Sulfur Compounds and Presence of Biofilm

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01616355
Enrollment
15
Registered
2012-06-11
Start date
2011-08-31
Completion date
2011-11-30
Last updated
2012-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Problems With Dentures

Keywords

denture, complete;, sodium hypochlorite;, disinfection;, surface roughness;, color stability.

Brief summary

The present study tried to integrate all aspects of denture care: patient satisfaction with the treatment, denture decontamination and base material defects after decontamination processing.

Detailed description

Considering that it is necessary to stipulate a simple and effective routine protocol for denture cleaning the aim of this study was to evaluate, in vivo, the efficacy of 0.5% sodium hypochlorite (NaOCl) as a denture cleanser and its effect on color stability and surface roughness of complete dentures. The patients' satisfaction with the denture cleaning method was also assessed.

Interventions

OTHERSodium hypochlorite immersion

Dentures daily immersion in a 0.5% sodium hypochlorite solution for 3 minutes.

Sponsors

University of Campinas, Brazil
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* complete denture wearers; adequate general health conditions * ability to comply with the experimental protocol * time of denture use: at least one year prior the study * denture base material: heat-polymerized acrylic resin.

Exclusion criteria

* the use of antifungal agents or antiseptic mouthwashes during the pre-experimental and experimental period.

Design outcomes

Primary

MeasureTime frameDescription
Microorganisms reductionBaseline, 30, 60 and 90 daysQuantitative analysis of total microorganisms and Candida spp. Samples for culture were collected from dentures and saliva.
Changes in base acrylic resinBaseline, 30, 60 and 90 daysColor stability and surface roughness evaluation

Secondary

MeasureTime frame
Patients' satisfaction with the denture cleaning protocol30, 60 and 90 days

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026