Assessment of Hemodynamic Response in Cardiopulmonary Bypass Graft After Cardiopulmonary Bypass Using Transesophegeal Echocardiography

Assessment and Hemodynamic Response in CABG After Cardiopulmonary Bypass Using Intraoperative Transesophegeal Echocardiography

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01616069

Enrollment

Registered

2012-06-11

Start date

2012-02-29

Completion date

2013-12-31

Last updated

2015-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiopulmonary Bypass Graft

Keywords

CABG, Echocardiography, Heart Failure, Heart Function

Brief summary

This is a double blind randomization study, assessing hemodynamic response in patients who underwent a cardiopulmonary bypass graft (CABG) with cardiopulmonary bypass (CPB) using intraoperative trasnesophageal echocardiography (TEE) to know what inotropic drug will be batter to improve the heart function. Epinephrine, milrinone, dobutamine and levosimendan will be assessment.

Interventions

DRUGepinephrine and levosimendan

epinephrine (0,06mcg/kg/min), levosimendan (0,2 mcg/kg/min)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

45 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Sinusal ritmus * EF \> 35% * Elective CABG surgery

Exclusion criteria

* No accept * Severe valvular regurgitation or stenoses * Chest pain * Cardiogenic shock

Design outcomes

Primary

Measure	Time frame	Description
Systolic and diastolic heart function	Two years	Assessment the systolic and diastolic heart function

Secondary

Measure	Time frame	Description
Mortality after CABAG	Two years	Assessment mortality after CABAG

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 3, 2026