Respiratoy Failure Requiring NIV Treatment
Conditions
Brief summary
Comparison of the effects of 4 ventilators dedicated to NIV (2 home ventilators and 2 ventilators designed for NIV) on patient-ventilator synchrony and comfort in patients admitted in the intensive care unit for respiratory failure and treated with NIV.
Interventions
DEVICEV-PAP III ventilator
DEVICEStellar 150 ventilator
DEVICEBiPAP vision ventilator
DEVICEV60 ventilator
Sponsors
University of Lausanne Hospitals
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* respiratory failure
Exclusion criteria
* Severe hypoxemia requiring an FiO2 \> 0.6 * Hemodynamic instability : defined as a variation of \> 20% in mean arterial pressure (MAP) and heart rate (HR) during the previous 2 hours; the need for high doses of catecholamines (namely \> 0.5 mcg/kg/min) and/or the need of major volume resuscitation (more than 2 liters of fluids in 2 hours) * Impaired consciousness or absence of patient cooperation; * Facial or laryngeal lesions contraindicating the use of NIV; * Poor short term prognosis. * Age \< 18 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient-ventilator synchrony | — | Patient-ventilator synchrony will be assessed breath by brath on the basis of airway pressure, flow and diaphragmatic electrical activity recordings. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| comfort of patient under NIV | — | Patient's confort during NIV will be assessed using a visual analogic scale. |
| Ventilatory parameters | — | Tidal volume, respiratory rate, inspiratory time, expiratory time and maximal and mean airway pressure will be measured from the continuous recording of airway pressure and flow. |
Countries
Switzerland
Outcome results
None listed