Abnormal Uterine and Vaginal Bleeding, Unspecified, Infertility, Recurrent Abortion
Conditions
Keywords
Office hysteroscopy, Cervical priming, Misoprostol
Brief summary
Misoprostol is an effective agent for cervical priming before office hysteroscopy, vaginal route is the best, optimum dose not yet known.
Detailed description
The investigators will compare between 2 different doses of vaginal misoprostol, group (1) 200 ug, group (2) 400 ug, 3hours prior to office hysteroscopy , Infertile patient, patients with abnormal bleeding and patient with recurrent abortion Outcome measure: pain score, easiness of the procedure, procedure time, complications
Interventions
DRUGMisoprostol
200 ug
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Female patient pre- or postmenopausal undergo office hysteroscopy. * Age: from 20 to 60. * BMI between 18 and 30.
Exclusion criteria
* PID or * Heavy uterine bleeding * Cervical malignancy. * Symptoms suggestive of endometriosis . * Any cervical abnormality such as pinhole cervix that would obviate passage of a catheter through the cervix.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain score | 1year | Pain score by VAS |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Easiness | 1year | ease of entry of the office hysteroscopy into the cervix recorded on a 5-point Likert scale: very difficult= 1, difficult = 2, fair = 3, easy = 4, and very easy = 5; |
| Duration of the procedure | 1year | Duration of hysteroscopy in seconds |
Countries
Egypt
Outcome results
None listed