Patients at Risk for Melanoma
Conditions
Keywords
Cohort, Melanoma, targeted screening, risks function, cost effectiveness
Brief summary
Melanoma is nowadays an important public health problem because its growing incidence. Mass screening for melanoma is not recommended worldwide because of its low cost-effectiveness. Nevertheless targeted screening for patients at high risk for melanoma is promoted. This study is designed to assess the effectiveness and the acceptability of a melanoma targeted screening of melanoma, to estimate the risk function to develop a melanoma among patients at high risk according to the SAMScore and to estimate the ratio cost/ efficacy of the melanoma targeted screening. A cohort of 7700 patients is carried out in 2 departments covered by a registry of cancers. The recruitment had began in April 2011. Patients assessed at high risk according to the SAMScore were proposed a skin examination by their GP every year.
Interventions
OTHERSAMScore questionnaire
Patients assessed at high risk according to the SAMScore
Sponsors
Nantes University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients more than 18 years old, * consulting their GP, * assessed at risk for melanoma according to the SAMScore * signed the consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence ratios between those of the COPARIME cohort and those of the general population. | 5 years | Number of melanomas detected / Number of patients at high risk of melanoma defined by our selection tool. |
Secondary
| Measure | Time frame |
|---|---|
| Probability to develop a melanoma at one year. | 1 years |
| Cost ratio for a screened melanoma. | 5 years |
Countries
France
Outcome results
None listed