Platelet Inhibition and Bleeding in Patients Undergoing Non-Cardiac Surgery

Does Platelet Inhibition Predict Surgery Related Bleeding in Patients Undergoing Non-Cardiac Surgery During Dual Antiplatelet Therapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01606865

Acronym

BIANCA

Enrollment

207

Registered

2012-05-28

Start date

2010-09-30

Completion date

2014-01-31

Last updated

2014-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Bleeding

Brief summary

The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* intake of Clopidogrel, Prasugrel, or Ticagrelor within the last 7 days * spontaneous bleeding or impeding surgery (major vascular surgery, intraperitoneal or intrathoracic surgery, ENT-surgery, orthopedic or trauma surgery, prostatic surgery)

Exclusion criteria

* concomitant medication with warfarin * renal insufficiency needing dialysis * concomitant therapy with GPIIB/IIIA Antagonists * expected duration of operation \>30min

Design outcomes

Primary

Measure	Time frame
increased risk of bleeding (according to TIMI definition)	24hours postoperatively

Countries

Austria

Outcome results