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Trial of Effect of High-frequency Transcranial Magnetic Stimulation in the Management of Borderline Personality Disorder

A Sham-controlled Trial of Effect of High-frequency Transcranial Magnetic Stimulation in the Management of Borderline Personality Disorder Patients

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01602497
Enrollment
40
Registered
2012-05-21
Start date
2012-02-29
Completion date
2012-12-31
Last updated
2012-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Borderline Personality Disorder

Keywords

Borderline personality disorder, repetitive transcranial magnetic stimulation

Brief summary

This study is going to evaluate the effects of repetitive transcranial magnetic stimulation (rTMS) on Borderline Personality Disorder patients symptoms.

Detailed description

There is a great body of literature about the positive effects of rTMS therapy on various psychiatric disorders. In this study we are going to evaluate the effects of high-frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC)region in borderline personality disorder (BPD) patients. patients will be assessed by subjective measures for BPD.

Interventions

DEVICErTMS

Patients undergone 10 session of high-frequency rTMS therapy over their left DLPFC

DEVICEsham rTMS

Patients will undergo ten session of sham rTMS.

Sponsors

Tehran University of Medical Sciences
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Clinically diagnosed borderline personality disorder according to DSM IV.

Exclusion criteria

* Epilepsy * Any metal device * Psychotic disorders * Bipolar mood disorder type 1

Design outcomes

Primary

MeasureTime frameDescription
Patients' reportsChange from baseline to two weekschanges in subjective measures from baseline to tenth day of treatment

Secondary

MeasureTime frameDescription
patient's reportChange from baseline to 1 monthchange in subjective measures from baseline to 1 month after treatment
Patient's reportChange from baseline to 3 monthchange in subjective measures form baseline to 3 month after treatment

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026