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Odense Fallers and Osteoporosis Study

Odense Fallers and Osteoporosis Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01600547
Acronym
OFOS
Enrollment
322
Registered
2012-05-17
Start date
2012-05-31
Completion date
2014-12-31
Last updated
2014-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Accidental Falls, Disability, Osteoporosis

Brief summary

Osteoporosis and falls occur with increasing frequency among the elderly. Osteoporosis and fall increases the risk of fracture. Falls in the elderly are associated with a high morbidity and mortality with potentially life-threatening consequences of falls including fractures. Besides fracture fall may cause long term problems such as disability fear of falling and loss of independence. Today osteoporosis is diagnosed by bone scan of the hip and spine. The investigators want to investigate whether other more accessible and less expensive testing methods can be used to diagnose osteoporosis. Additionally, the investigators will examine the incidence of osteoporosis among the elderly in the municipality of Odense. Finally, the investigators would like to investigate the association between factors that can lead to falls and to investigate the performance of older and whether there are changes in functional ability over time.

Detailed description

Study Objectives 1. To define the prevalence of osteoporosis in a falls clinic population, and compare it with two aged matched control groups - fallers not attending the falls clinic and non-fallers. 2. To evaluate the usefulness of peripheral bone scanning techniques in a falls clinic population. 3. To determine the prevalence of vertebral fractures in a falls clinic population and compare it with two aged matched control groups - fallers not attending the falls clinic and non-fallers 4. To investigate functioning, disability, health related quality of life and perceived need for rehabilitation in a falls clinic population including variation in a one year period, and compare it with two aged matched control groups - fallers not attending the falls clinic and non-fallers.

Interventions

None listed

Sponsors

Odense University Hospital
CollaboratorOTHER
University of Southern Denmark
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
65 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Women aged 65 years or over attending the falls clinic \*(There will be no upper age limit to recruitment). * Those capable of giving Informed consent.

Exclusion criteria

* Patients under the age of 65 years. * Men. * Patients unwilling to give informed consent. * Cognitively impaired people who are not capable of giving consent. * Patients who are not mobile enough to be helped onto a DXA scan table with help

Design outcomes

Primary

MeasureTime frameDescription
Basis mobilityOne yearTime up and go, Chair stand, Bergs balance scale, Avlunds scale, gait speed and dual-task will be used
Fear of fallingOne yearThe Falls Efficacy scale - international will be used
Muscle strength in upper and lower extremitiesOne yearA dynamometer will be used
Bone mineral density using DXA of hip and spine regions (Hologic machine)baseline
Prevalence of vertebral fractures using instant vertebral assessment mode (IVA) of the DXA machine (Hologic machine)baseline
Bone mineral density of the phalanges using radiographic absorptiometry (Alara Metriscan machine)baseline
Broad band ultrasound attenuation of the heel using the heel ultrasound machine (Lunar Achilles machine)baseline
Fall incidencesone year
Mental health stateone yearMeausered by Mini Mental State Examination (MMSE)
Health related quality of lifeone yearSelf Reporting Questionnaire will be used
Perceived needone yearSelf Reporting Questionnaire

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026