Neonatal Hyperbilirubinemia
Conditions
Keywords
Neonatal hyperbilirubinemia, Follow-up, Motor development, Hearing, Executive function
Brief summary
The objective of this study was to investigate whether infants with total serum bilirubin \> 450 umol/L in the neonatal period and no symptoms or no more than early acute bilirubin encephalopathy develop long term sequelae with impairment of motor development, hearing and executive function compared with a control group.
Detailed description
Children in both the exposed and the non-exposed group were examined by use of the MABC-2 and pure tone audiometry by the responsible examiner for the study, Pernille Vandborg, MD. The aim was to see whether the exposed group suffered any long term sequelae to the extreme neonatal hyperbilirubinemia, i.e. impaired motor development or hearing impairment, compared to a control group. The examinations took place at the local hospital.
Interventions
PROCEDUREMovement assessment battery for children - 2
A standardised test developed to identify developmental difficulties in children.
Sponsors
University of Aarhus
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
5 Years to 10 Years
Healthy volunteers
No
Inclusion criteria
* Gestational age \> 35 weeks * Total serum bilirubin \> 450 umol/L in the neonatal period * Born in the period 01.01.2000 - 31.12.2005
Exclusion criteria
* Acute intermediate or advanced bilirubin encephalopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Motor development | Age 5-10 years | Delayed motor development for children in the exposed group compared to children in the non-exposed group |
Outcome results
None listed