Male Infertility
Conditions
Keywords
Male infertility
Brief summary
How daily consumption of pomegranate juice affects the concentration, morphology or motility of sperm in healthy men.
Detailed description
To determine, in this pilot study, whether daily consumption of pomegranate juice (POM) affects the concentration, morphology or motility of sperm in healthy men. The purpose of the present pilot study is to examine the hypothesis that POM may improve semen parameters in men.
Interventions
DIETARY_SUPPLEMENTPomegranate juice
Pomegranate juice
Sponsors
POM Wonderful LLC
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* 12 healthy men aged 18-40 * normal sperm counts
Exclusion criteria
* History of undescended testes or surgery to the scrotal contents, * History of marijuana or alcohol abuse, hot tub usage at least 3 months prior to entry into the study * No alpha adrenergic medications within two weeks of entry into the study, * No anabolic steroid use, * No anticholinergic or antimuscarinic drugs, use of colchicine, cimetidine, sulfasalazine, antipsychotics, antidepressants, immunosuppressive drugs prior use of any chemotherapeutic drugs, or UTI on screening visit.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in sperm counts | Baseline and 6 months | The primary outcome will be change in sperm counts relative to baseline with and without POM. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Sperm count | 6 months | The secondary outcome will be change in sperm counts relative to baseline with and without POM. |
Countries
United States
Outcome results
None listed