Risk Factor Analysis for Developing Metabolic Syndrome in Korean Adults

Conditions

Metabolic Syndrome, Atherosclerosis

Brief summary

In Asia, the prevalence of metabolic syndrome have been dramatically increased. Therefore, the investigators intend to the collect the blood sample, laboratory, anthropometric, and body composition parameters prospectively to examine the risk factors of metabolic syndrome. Furthermore, the investigators will collect the data of carotid IMT and branchial ankle pulse wave velocity to clarify the metabolic risk factors of atherosclerosis.

Hye Jin Yoo, Soon Young Hwang, Ju-Hee Choi, Hyun Jung Lee, Hye Soo Chung et al. (11 authors)

PLoS ONE2017-04-0472 citations

10.1371/journal.pone.0174717

Waist-to-hip ratio is better at predicting subclinical atherosclerosis than body mass index and waist circumference in postmenopausal women.

Lee HJ, Hwang SY, Hong HC, Ryu JY, Seo JA, Kim SG, Kim NH, Choi DS, Baik SH, Choi KM, Yoo HJ.

2015-01-1218 citations

10.1016/j.maturitas.2014.12.015

Association of metabolically abnormal but normal weight (MANW) and metabolically healthy but obese (MHO) individuals with arterial stiffness and carotid atherosclerosis.

Yoo HJ, Hwang SY, Hong HC, Choi HY, Seo JA, Kim SG, Kim NH, Choi DS, Baik SH, Choi KM.

2014-03-1652 citations

10.1016/j.atherosclerosis.2014.02.033

Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris

Kyung Mook Choi, Soon Young Hwang, Ho Chel Hong, Hae Yoon Choi, Hye Jin Yoo et al. (8 authors)

Cardiovascular Diabetology2014-01-1366 citations

10.1186/1475-2840-13-14

Relationship Between Sarcopenia and Nonalcoholic Fatty Liver Disease: The Korean Sarcopenic Obesity Study

Ho Cheol Hong, Soon Young Hwang, Hae Yoon Choi, Hye Jin Yoo, Ji A Seo et al. (10 authors)

Hepatology2013-08-31381 citations

10.1002/hep.26716

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Apparently healthy people who underwent medical routine check up in Korea Health Promotion Center. * age \> 20 years

Exclusion criteria

* History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization) * Stage 2 hypertension * Severe renal or hepatic disease

Design outcomes

Primary

Measure	Time frame
The impact of various cardiovascular risk factors (inflammatory markers, hepatokines, adipokines, body composition parameters) for developing metabolic syndrome in prospective design	36months

Secondary

Measure	Time frame
The relationship of various cardiovascular risk factors (inflammatory markers, hepatokines, adipokines, body composition parameters) with metabolic syndrome and atherosclerosis measured by baPWV and carotid IMT in cross sectional design	36months

Countries

South Korea

Outcome results