Routine Ultrasound Screening in the Third Trimester

Third Trimester Routine Ultrasound in Low-risk Pregnancies : Comparison of Two Timing Periods Procedure for Screening Intrauterine Growth Restriction

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01594463

Acronym

RECRET

Enrollment

3760

Registered

2012-05-09

Start date

2012-05-31

Completion date

2016-03-31

Last updated

2016-05-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal Growth Retardation, High-Risk Pregnancy

Keywords

Intrauterine growth restriction, Screening, Ultrasound, Perinatal morbidity, Maternal complications

Brief summary

Late intrauterine growth restriction is infrequently diagnosed with an overall sensitivity of 40 % in low-risk pregnancies. In addition, late intrauterine growth restriction may be associated with intrauterine death and poor neonatal outcomes i.e. birth asphyxia and hospitalization in intensive care unit. The investigators hypothesis that a later third trimester routine ultrasound may be more accurate to diagnose late intrauterine growth restriction.

Interventions

OTHERultrasound examination

ultrasound examination between week 30+1 weeks to 31+6 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Accurate gestational dating using crown-rump length at 11-14 weeks * Singleton pregnancy * Primiparity * Normal First trimester (11-14 weeks) and second trimester (20-25 weeks) scans * Maternal age \> 18 years * No maternal opposition for the study

Exclusion criteria

* Maternal diseases i.e. chronic renal disease, hypertension, diabetes, collagen vascular disease, antiphospholipid syndrome * Pregnancies with congenital anomalies or foetal growth restriction diagnosed before 30 weeks of gestation

Design outcomes

Primary

Measure	Time frame	Description
Number of small for gestational age infant screened by a routine ultrasound in the third trimester (sensitivity).	At birth	SGA infant and intrauterine growth restriction are defined using a threshold below the tenth percentile for customized birth weight or customized estimated birth weight.

Secondary

Measure	Time frame
Number of neonate with a customized birth weight upper the tenth percentile adequately screened by a routine ultrasound in the third trimester (specificity).	At birth
Number of prenatal consultations, ultrasound scans performed, maternal hospitalization, labor induction, and caesarean section induced by the third trimester routine ultrasound	After the delivery
Maternal complications and neonatal outcomes.	In the postpartum period

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026