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Caffeine and Sodium Citrate Ingestion

Effects of Caffeine and Sodium Citrate Ingestion in 1500m Wheelchair Racing Athletes

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01591226
Enrollment
9
Registered
2012-05-03
Start date
2012-02-29
Completion date
2012-09-30
Last updated
2016-11-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dietary Supplements, Heart Rate/Drug Effects, Lactic Acid/Metabolism, Physical Education and Training/Methods, Wheelchairs

Keywords

caffeine, sodium citrate, exercise performance, wheelchair athletes, 1500m

Brief summary

A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects. The aim of the study is to investigate whether caffeine or sodium citrate ingestion could enhance performance in spinal cord injured wheelchair athletes. It is a double blind, placebo controlled and randomized study.

Detailed description

The athletes have to complete four 1500m tests on a training roller. Before each treatment they get different supplementations. Once they get sodium citrate and a placebo, once caffeine and a placebo, once sodium citrate and caffeine and for the fourth treatment they get twice a placebo. Two hours after starting with the supplementation they have to complete the 1500m as fast as possible. Time to complete 1500m, blood pH, plasma bicarbonate, sodium concentration, heart rate, oxygen consumption, blood lactate concentration and rate of perceived exertion (RPE) were measured.

Interventions

DIETARY_SUPPLEMENTCaffeine

gelatine capsule 6mg/kg bodyweight 60min prior test

DIETARY_SUPPLEMENTSodium Citrate

0.5g/kg bodyweight diluted in 7dl water ingested 120-90min prior test

DIETARY_SUPPLEMENTMannitol

gelatine capsule filled with mannitol (100mg per capsule) ingested 60min prior test

DIETARY_SUPPLEMENTSodium Chloride

sodium chloride diluted in 7dl water 0.045g/kg bodyweight 120-90min prior test

Sponsors

Swiss Paraplegic Research, Nottwil
Lead SponsorNETWORK

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes

Inclusion criteria

* wheelchair athletes * national team * category T53 and T54

Exclusion criteria

* medicated * pregnant (for women) * cardiovascular and respiratory diseases

Design outcomes

Primary

MeasureTime frameDescription
Time3 weeksTime to complete 1500m

Secondary

MeasureTime frameDescription
Lactate Concentrationduring the 3 weeks study phase1min before starting the warm up, 15s after the end of the warm up, 15s after completing the test, 2min/4min/6min/8min/10min after the test
blood pH, sodium concentration and plasma bicarbonateduring the 3 weeks of study phase1min before starting with the ingestion of the fluid, immediately before starting the warm up, just immediately before starting the 1500m test.
Heart Rateduring study phase of 3 week (4 tests)Heart Rate measured from 2min before the test until 5min after the 1500m-test.
rating of gastrointestinal stressduring the 3 weeks of study phase1min before starting to drink the fluid, 2min before starting with the warm up, 2min before the test and 2min after having completed the 1500m
Rating of Perceived Exertion (RPE)during the 3 weeks of study phase15s after the end of the warm up, 15s after having completed the 1500m
Oxygen Consumptionduring 3 weeks of study phaseoxygen consumption (VO2(ml/min/kg), VCO2(ml/min), RER (VCO2/VO2)) starting of the measurement is 2min before the start of the 1500m and ends 2min after having completed the 1500m

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026