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Prevalence of and Factors Associated With Metabolic Syndrome in Schizophrenia

Prevalence of and Factors Associated With Metabolic Syndrome in Patients With Schizophrenia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01587521
Enrollment
80
Registered
2012-04-30
Start date
2012-01-31
Completion date
2016-06-30
Last updated
2016-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, Metabolic Syndrome, Quality of Life

Keywords

Metabolic syndrome, Prevalence, Quality of life, Depression, Antipsychotics

Brief summary

Patients with schizophrenia are more likely to have metabolic syndrome compared to general population. The criterion for metabolic syndrome in Asian people including: elevated waist circumference (male ≥ 90cm, female ≥ 80cm), elevated triglycerides ≥ 150mg/dL, reduced HDL cholesterol: male \< 40mg/dL, female \< 50mg/dL, elevated blood pressure: ≥ 130/85 mmHg, elevated fasting glucose: ≥ 100mg/dL. Several factors have been found to be associated with metabolic syndrome in schizophrenia, e.g. age, antipsychotic drugs, smoking, family history of metabolic disorder, stress, and quality of life. However, little is known about the prevalence of and factors associated in Asian. This study aimed to: 1. Identify the prevalence of metabolic syndrome in patients with schizophrenia. 2. Identify the factors associated with metabolic syndrome in patients with schizophrenia.

Detailed description

Patients with schizophrenia are more likely to have metabolic syndrome compared to general population. The criterion for metabolic syndrome in Asian people including: elevated waist circumference (male ≥ 90cm, female ≥ 80cm), elevated triglycerides ≥ 150mg/dL, reduced HDL cholesterol: male \< 40mg/dL, female \< 50mg/dL, elevated blood pressure: ≥ 130/85 mmHg, elevated fasting glucose: ≥ 100mg/dL. Several factors have been found to be associated with metabolic syndrome in schizophrenia, e.g. age, antipsychotic drugs, smoking, family history of metabolic disorder, stress, and quality of life. However, little is known about the prevalence of and factors associated in Asian. This study aimed to: 1. Identify the prevalence of metabolic syndrome in patients with schizophrenia. 2. Identify the factors associated with metabolic syndrome in patients with schizophrenia. Method This study is a cross-sectional study conducting at the Faculty of Medicine, Chiang Mai University. Eighty participants will be recruited with the inclusion criteria of having diagnosed with schizophrenia according to DSM-IV-TR and aged 18 years or over. The exclusion criterion is having organic brain syndrome. Measurements PANSS CDSS WHOQOL-BREF-THAI

Interventions

None listed

Sponsors

Chiang Mai University
Lead SponsorOTHER

Study design

Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosis of schizophrenia according to DSM-IV-TR * Aged 18 years-old or over

Exclusion criteria

* Having organic brain syndromes

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026