The Effect of Endurance Training in Patients With Prostate Cancer

The Effect of Endurance Training on PSA Doubling Time, Body Composition, Insulin Sensitivity and Inflammation in Patients With Prostate Cancer

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01584960

Enrollment

Registered

2012-04-25

Start date

2008-04-30

Completion date

2012-05-31

Last updated

2013-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body Composition, Beneficial, Insulin Sensitivity, Prostate Cancer

Brief summary

The aim of the present study is to investigate the effect of endurance on PSA doubling time in prostate cancer patients with an elevation in PSA following radical prostatectomy for localized cancer. Furthermore, underlying mechanisms such as reduction in inflammatory markers and improvement in insulin sensitivity and body composition are investigated.

Interventions

BEHAVIORALendurance training

2 years of home-based endurance training

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Prostate cancer patients with an increase in PSA following radical prostatectomy

Exclusion criteria

* severe cardiovascular disease * severe arthritis * severe neuropathy * severe hypertension * therapy with antidiabetic agents * other treatment for prostate cancer than radical prostatectomy

Design outcomes

Primary

Measure	Time frame
PSA doubling time	2 years

Secondary

Measure	Time frame
Insulin sensitivity, body composition and inflammation status	0 months, 6 months and 24 months of training

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026