Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar

Evaluation of Platelet Rich Fibrin Efficacy on Reduction of Periodontal Problems

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01583491

Enrollment

Registered

2012-04-24

Start date

2011-12-31

Completion date

2012-05-31

Last updated

2012-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastication Disorder

Keywords

platelet rich fibrin, mandibular third molar, periodontal problem

Brief summary

The purpose of this study is to determine the influence of platelet rich fibrin to reduction of periodontal problems after surgical removal of third molar.

Detailed description

After extraction or surgical removal of third molar, a deep bony pocket created behind the second molar specially in the mandible. For reduction of this problem, investigators, needed to acceleration tissue healing. For this purpose, investigators used platelet rich fibrin (autologous) and followed patient for 3 months.

Interventions

PROCEDUREautologous platlet rich fibrin

one dose immediate after surgery

PROCEDUREone side in control group

control group insert any things after surgery

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* have 2 impacted third molars

Exclusion criteria

* periodontal disease * history of periodontal surgery

Design outcomes

Primary

Measure	Time frame
Measurement of periodontal pocket depth at mid buccal, disto buccal and distolingual of mandibular second molar	4 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026