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Changes in Habitual Physical Activity and Inactivity

Changes in Physical Activity and Inactivity During a 12-week Exercise Training and/or Sedentary Time Intervention

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01580930
Acronym
START
Enrollment
57
Registered
2012-04-19
Start date
2010-03-31
Completion date
2011-05-31
Last updated
2012-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Habitual Physical Activity, Sedentary Time

Keywords

physical inactivity, exercise training, sedentary time, habitual physical activity

Brief summary

The purpose of this study is to determine if individuals involved in exercise training change habitual activity and inactivity behavior outside of exercise training. Eligible participants were randomly assigned to one of four groups: control, exercise training, sedentary time reduction, or exercise training plus sedentary time reduction. It was hypothesized that participants in the exercise training group will compensate for exercise training by reducing free-living physical activity behavior and increasing sedentary time. Participant free-living behavior was monitored for one week at baseline, 3, 6, 9 and 12 weeks using an activPAL wearable monitor.

Interventions

BEHAVIORALexercise training

12 weeks, 5 days of week, 40 min per session of exercise training

BEHAVIORALsedentary time reduction

participants provided with strategies to decrease sitting

BEHAVIORALexercsie training plus sedentary time reduction

12 weeks of exercise training (5 days a week, 40 min per session) plus given strategies for reducing sitting time

Sponsors

National Heart, Lung, and Blood Institute (NHLBI)
CollaboratorNIH
University of Massachusetts, Amherst
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

Eligible participants were those at increased risk of cardiovascular disease, based on meeting two of the following three criteria: 1. Pre-hypertensive: resting blood pressure between 125-160 mm Hg systolic and/or 85-100 mm Hg diastolic, 2. overweight/obese: body mass index (BMI) between 25 and 45 kg∙m-2, 3. high central adiposity: as defined by elevated natural waist circumference (\> 102 cm \[males\] \> 88cm \[females\]), a surrogate measure of visceral fat 4. low aerobic fitness (VO2 peak ≤ 50th percentile of age and sex specific norms) 5. exercising less than three days per week for less than 20 minutes per session for the preceding six months

Exclusion criteria

* major orthopedic limitations, * wheelchair use or musculoskeletal problems that affected mobility, * life-threatening illness (e.g., terminal cancer), * chronic diseases (e.g., diagnosed heart disease, diabetes, emphysema) or * any condition for which a physician did not recommend exercise. Participants were excluded if they had gastric bypass or lap-band surgery within the last year, were taking medication for type II diabetes (e.g. metformin) or beta-blocker medication for high blood pressure.

Design outcomes

Primary

MeasureTime frameDescription
change from baseline in sedentary time at 12 weeks12 weeksMeasure is based on data collected with a wearable monitor that assesses time spent sitting/lying, standing, and walking
change from baseline in sedentary time at 3 weeks3 weeksMeasure is based on data collected with a wearable monitor that assesses time spent sitting/lying, standing, and walking
change from baseline in sedentary time at 6 weeks6 weeksMeasure is based on data collected with a wearable monitor that assesses time spent sitting/lying, standing, and walking
change from baseline in sedentary time at 9 weeks9 weeksMeasure is based on data collected with a wearable monitor that assesses time spent sitting/lying, standing, and walking

Secondary

MeasureTime frameDescription
change from baseline in physical activity at 3 weeks3 weekswearable monitor (activPAL) assesses number of steps, MVPA
change from baseline in physical activity at 6 weeks6 weekswearable monitor (activPAL) assesses number of steps, MVPA
change from baseline in physical activity at 9 weeks9 weekswearable monitor (activPAL) assesses number of steps, MVPA
change from baseline in physical activity at 12 weeks12 weekswearable monitor (activPAL) assesses number of steps, MVPA

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026