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Effects of Berries on Post-meal Blood Sugar

Effects of Berries on Postprandial Glycemic Responses to Sucrose and Starch

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01580150
Acronym
SOMA
Enrollment
20
Registered
2012-04-18
Start date
2009-11-30
Completion date
2012-01-31
Last updated
2012-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Glucose, Postprandial, Blood Insulin, Postprandial, Hyperglycemia

Keywords

Berries, Starch, Sucrose, Glucose, Insulin, Postprandial

Brief summary

The purpose of this study is to investigate whether berries are effective in lowering blood glucose and insulin responses to meals containing starch or sucrose.

Detailed description

Berries are rich sources of various polyphenols which may be beneficial in the regulation of blood glucose. In vitro and animal studies have shown that polyphenols and polyphenol-rich extracts of foods, including berries, may inhibit digestion and absorption of carbohydrates and thereby suppress postprandial glycemia. However, current evidence on the effects of berries on postprandial glycemic responses in humans is limited. The purpose of this study is to investigate the effects of berries on postprandial glycemic responses (blood glucose and insulin) to starch or sucrose in healthy subjects. It consists of five substudies each of which includes 2-4 meals with different berry species typically consumed in Finland and a reference meal without berries. The following combinations of carbohydrates and berries are studied: * Studies 1-2: white wheat bread (starch) is consumed with several berry species * Study 3: white wheat bread or rye bread is consumed with a mixture of berries * Study 4: sugar (sucrose) is consumed with berries and berry nectars * Study 5: a sugar-sweetened bakery product (starch + sucrose) is consumed with berries and berry nectar.

Interventions

OTHERBerries

Meals containing starch (bread) or sucrose are consumed with berries (150 g) or berry nectars (300 mL).

OTHERNo berries

Meals containing starch (bread) or sucrose are consumed without berries.

Sponsors

Marjukka Kolehmainen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Age
25 Years to 69 Years
Healthy volunteers
Yes

Inclusion criteria

* BMI 20-28 kg/m2 * normal fasting plasma glucose

Exclusion criteria

* Smoking * Diabetes or other chronic disease * Antibiotic medication within the past 3 months * Blood donation within the past month

Design outcomes

Primary

MeasureTime frame
Plasma glucose0, 15, 30, 45, 60, 90, 120 minutes post-meal
Plasma insulin0, 15, 30, 45, 60, 90, 120 minutes post-meal

Secondary

MeasureTime frame
Plasma free fatty acids0, 15, 30, 45, 60, 90, 120 minutes post-meal

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026