Succinylcholine or Rocuronium for Rigid Bronchoscopy Under General Anesthesia

Interventional Rigid Bronchoscopy Under General Anesthesia: Influence of the Muscle Relaxant, Succinylcholine or Rocuronium, on the Quality of the Surgical Procedure

Status

Terminated

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01579864

Acronym

Broncho-SR

Enrollment

Registered

2012-04-18

Start date

2012-01-31

Completion date

2015-06-30

Last updated

2016-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Brief summary

Myorelaxation is generally used as a part of general anesthesia for interventional rigid bronchoscopy. Succinylcholine is most often used because its short duration of action but rocuronium can be used since sugammadex permits a rapid and complete reversal of the neuromuscular block. The aim of ths study is to compare both agents.

Interventions

DRUGsuccinylcholine

Succinylcholine 1 mg/kg and a second dose if necessary. Rocuronium 0,4 mg/kg can be used as a rescue

DRUGrocuronium

rocuronium 0,9 mg/kg with additional boluses of 0,3 mg/kg f necessary

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Caregiver)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients scheduled for an interventional rigid bronchoscopy under general anesthesia

Exclusion criteria

* pregnant woman or woman of childbearing age, * morbid obesity, * drug allergy,contra-indication to succinylcholine, rocuronium, sugammadex, propofol, remifentanil, * history of central neurological or brain damage, * psychotropic treatment, * pacemaker, * renal failure, * disease of the neuromuscular junction.

Design outcomes

Primary

Measure	Time frame	Description
Score of quality of the surgical procedure	one day	The quality of the surgical procedure is evaluated by the surgeon (composite score) who is unaware of the neuromuscular agent used (see Fuchs-Buder et al. Acta Anaesthesiol Scand 2007;51(7):789-808)

Secondary

Measure	Time frame	Description
Score of quality of anesthesia	one day	The quality of anesthesia is evaluated by the anesthesist in charge on a scale 0-30 (0-10 for the induction ; 0-10 for maintenance; 0-10 for recovery)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026