Effects of Salpingectomy During Laparoscopic Hysterectomy on Ovarian Function

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01578759

Enrollment

Registered

2012-04-17

Start date

2012-04-30

Completion date

2013-10-31

Last updated

2017-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic Hysterectomy

Keywords

ovarian function tests

Brief summary

The purpose of this study is to assess the feasibility of performing a randomized clinical trial evaluating the effect of salpingectomy (removal of the fallopian tubes) during laparoscopic hysterectomy on ovarian function. The hypothesis is that removal of the tubes can prevent diseases of the fallopian tubes such as infection, hydrosalpinx (fluid-filled tubes)and additional invasive procedures such as further imaging work-ups and further surgery related to the tubes.

Interventions

PROCEDURESalpingectomy

Removal of the fallopian tubes

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Women ages 18-45 scheduled for laparoscopic hysterectomy with planned preservation of both ovaries.

Exclusion criteria

* Carrier for the gene that codes for breast cancer type 1 susceptibility protein (BRCA1) or the gene that codes for breast cancer type 2 susceptibility protein (BRCA 2). * Personal history of gynecologic cancer * Pregnancy * Non-English speaking * Unable to provide informed consent

Design outcomes

Primary

Measure	Time frame
Change from baseline in ovarian function as measured by Anti-Mullerian Hormone (AMH)	AMH blood samples collected prior to surgery at day 1 (the day of the surgery) and at 1 and 3 months after day 1.

Secondary

Measure	Time frame	Description
Patient demographics	Prior to surgery	The following routinely collected information will be included in the data analysis: age, body mass index, and surgery indication.
Patient surgical outcomes	Postoperatively on day 1	The following surgical outcomes will be collected postoperatively: total operating time, estimated blood loss, surgical complications, and surgical pathology.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026