A Comparative Study of Effects of Berry and Grain Products on Postprandial Glycemic Response in Healthy Subjects

A Clinical, Randomized, Comparative Study of Effects of Berry and Grain Products on Postprandial Glycemic Response in Healthy Subjects

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01575509

Enrollment

Registered

2012-04-11

Start date

2012-03-31

Completion date

2012-06-30

Last updated

2012-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

This study aims to determine the 2 hour glycemic responses of two bread products and one dried lingonberry product. The average postprandial response of each product is compared with glycemic response after ingestion of control solution with a similar carbohydrate content (glucose, glucose-fructose) as the provided by the respective test product.

Interventions

OTHERBerry product

Sugar infused dried lingonberry

OTHERBread product

Brown bread

OTHERGlucose control solution

Glucose solution with a corresponding amount of carbohydrates as provided by the bread test products

OTHERGlucose-fructose control solution

Control solution with a similar carbohydrate content as provided by the dried lingonberry test product

Study design

Allocation

Intervention model

SINGLE_GROUP

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* voluntary given written concent for participation in research * healthy man or woman, age between 18 and 65 years * regular eating * Body Mass Index 18,5 - 29,9 kg/m2

Exclusion criteria

* diabetes * gastrointestinal diseases * hepatic, kidney, pancreas or thyroid disease or disorder * arthritis * pregnancy or breast feeding * smoking * allergy * severe diseases * blood donation

Design outcomes

Primary

Measure	Time frame	Description
The 2 hours glycemic responses to test products and control solutions	2 hours	Capillary blood samples are taken before and at 15, 30, 45, 60, 90 and 120 min after starting to eat the test products or control solutions for measurements of plasma glucose concentrations.

Secondary

Measure	Time frame	Description
The 2 hours insulinemic responses to dried lingonberry product and corresponding control solution	2 hours	Capillary blood samples are collected before and at 15, 30, 45, 60, 90 and 120 min after eating the lingonberry test product and glucose-fructose control solution. The serum insulin concentrations are analysed.
The incremental area under glucose curve (IAUC) of bread test products	2 hours	IAUC (mmol/l x min) is determined using the trapezoidal method for each subject and bread test product and corresponding glucose control solution.
Glycemic index (GI) of bread test products	—	The GI is calculated as a percentage of the glucose IAUC values of a bread product and a glucose control solution.

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026