Prevalence and Reversibility of Lung Hyperinflation in Asthma

Evaluation of the Prevalence and the Reversibility of the Lung Hyperinflation in Uncontrolled Persistent Asthmatic Patients With Dyspnea

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01573364

Acronym

Dist'air2

Enrollment

450

Registered

2012-04-09

Start date

2011-02-28

Completion date

2012-01-31

Last updated

2012-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma

Keywords

Distal Airways, Hyperinflation, Reversibility

Brief summary

The aim of this observational study is to evaluate the pulmonary hyperinflation and its immediate reversibility to a short acting beta2 agonist test in uncontrolled persistent asthmatic patients with dyspnea.

Detailed description

The other objectives are : * the evaluation of the hyperinflation defined by an increase of the residual volume (RV), * the observation of the relationship between the hyperinflation and the asthma characteristics, * the study of the improvement of the functional parameters after a reversibility test * the evaluation of the correlation between hyperinflation parameters evolution, chest tightness and dyspnea

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Patient with a diagnosis of uncontrolled persistent asthma (ACT \</= 19) or with an MRC score of dyspnea \>/= 1 * Patient requiring a check-up including a pulmonary function test by plethysmography with a reversibility test

Exclusion criteria

* Patient participating to an other clinical trial or having participated to a clinical trial with medicine in the last 3 months

Countries

France

Outcome results