Major Depression
Conditions
Keywords
Adolescent, Randomized Trial, Internet, Depressive Disorder, Primary Care, Prevention
Brief summary
The purpose of the study is to determine whether a culturally tailored, low-cost, primary care/internet based depression prevention intervention (CURB) is superior to wait-list control for African American and Hispanic youth in terms of depression-related outcomes. It is hypothesized that compared to teens in the wait-list control condition, teens in the CURB program will exhibit lower levels of depressed mood and/or more rapid changes in mood during the follow-up time.
Detailed description
Additional aims and hypotheses are provided here: Aim 2: To determine whether or not participants in the CURB primary care/Internet based depression prevention intervention will have a significantly lower cumulative incidence of any depressive episode at 3 months compared to adolescents in the usual care wait-list group. Hypothesis 2: Compared to youth in the wait-list control condition, youth in the CURB program will have a lower incidence of depressive episodes at 6 month follow-up. Aim 3: To determine whether CURB is sustainable in primary care from the perspective of health care professionals and primary care physicians in urban primary care settings. Hypothesis 3: We hypothesize that providers will rate the intervention (by component) feasibility, acceptability, willingness to perform intervention and sustainability \> 7 on a 1-10 scale (1, not feasible, 10 very feasible).
Interventions
BEHAVIORALCURB
The intervention is made up of 14 internet modules based on behavioral activation, cognitive behavioral therapy, and interpersonal psychotherapy as well as motivational interviews in the primary care setting (to enhance behavior change). It is suggested that an adolescent navigates through 2 modules a week. The motivational interviews with the physicians occur directly before and after the adolescent is exposed to the website (at baseline and 3 months) in the providers office. The parents of the enrolled adolescents are also invited to navigate through their own, 3 module, parent internet program.
Sponsors
Benjamin Van Voorhees, MD, MPH
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
13 Years to 17 Years
Healthy volunteers
Yes
Inclusion criteria
Adolescents: * Male and female African American and Latino/a youth ages 13 -17 years old. * Adolescents with depressed mood (\> 2 weeks duration) will be eligible unless they have already exceeded the diagnostic threshold for major depressive disorder or have a comorbid condition as defined in the
Exclusion criteria
. Parents: * Parent of eligible adolescents Primary Care Physicians (PCPs): * Physician at one of the four Mile Square Health Centers. Health Care Professionals: * Employee at one of the four Mile Square Health Centers.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The Center for Epidemiological Studies of Depression (CES-D) Scale | 0, 3, 6 months | Change in CESD from baseline Change in CESD scale between and within groups across the 6 months and for each assessment point |
Secondary
| Measure | Time frame |
|---|---|
| Cost effective outcome measures | 6 months |
| Vulnerability | 6 months |
| Protective factors | 6 months |
Countries
United States
Outcome results
None listed