Monocytosis and Culprit Vessel in STEMI Patients

Significance of Monocytosis and Culprit Vessel in Patients With Acute ST Elevation Myocardial Infarction

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01569646

Enrollment

226

Registered

2012-04-03

Start date

2008-04-30

Completion date

Unknown

Last updated

2012-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

STEMI

Keywords

monocytes, culprit vessels

Brief summary

Increased white blood cell count at the onset of an acute ST elevation myocardial infarction has been shown to be associated of increased incidence of heart failure and mortality. Now monocytes which are a subset of white blood cells may have a prognostic value for patients presenting with acute ST segment elevation myocardial infarction. A monocyte count of greater than 800/mm3 following acute myocardial infarction has been shown to be associated with increased incidence of left ventricular dysfunction. The investigators study would retrospectively collect data on patients with ST elevation myocardial infarction, looking for an association between high monocyte count and the culprit vessel causing the myocardial infarction. The investigators would also investigate whether monocytosis would be a marker of poor prognosis.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* STEMI

Exclusion criteria

* Patients on antibiotics and steroids

Design outcomes

Primary

Measure	Time frame
Association between monocyte count and culprit vessel	1 day

Secondary

Measure	Time frame
clinical outcomes of troponin and monocyte in stemi patients	0 - 6 months

Countries

United States

Outcome results