Dependence of LV Hemodynamics on Pacing Site

Characterization of LV Hemodynamics During Epicardial and Endocardial Pacing

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01564173

Enrollment

Registered

2012-03-27

Start date

2012-06-30

Completion date

2016-03-31

Last updated

2019-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure

Brief summary

The purpose of this study is to evaluate the effects of epicardial and endocardial pacing at each side of the left ventricular (LV) segments on cardiac hemodynamics in patients with impaired LV function undergoing epicardial ablation and mapping procedure. Hemodynamic function will be assessed during a pacing protocol with a pressure catheter inserted in the LV.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patient is already indicated for epicardial mapping and ablation of arrhythmia(s) utilizing a transcutaneous subxiphoid approach * Be in sinus rhythm * Have LVEF \< 40% * Have the ability to provide informed consent for study participation and be willing and able to comply with the CIP (Clinical Investigational Plan) described evaluations

Exclusion criteria

* Have permanent AF * Have pericardial disease * Have a recent myocardial infarction within 40 days prior to enrollment * Have undergone cardiac surgery or coronary revascularization procedure within 3 months prior to enrollment or be scheduled for such procedures * Have had a recent CVA or TIA within 3 months prior to enrollment * Be less than 18 years of age * Be pregnant

Design outcomes

Primary

Measure	Time frame	Description
Invasive Dp/dt Max	Acute E.P. Procedure	Variation on invasive Dp/dt max during dedicated pacing site

Countries

France

Outcome results