Colonoscopy, Esophagoscopy Techniques
Conditions
Keywords
colonoscopy, bowel preparation, tolerability, EGD-assisted
Brief summary
Adequate bowel preparation is of critical importance for colonoscopy. Particularly among hospitalized patients, inadequate bowel preparation for colonoscopy may arise due to patient intolerance to prescribed laxative regimen, elderly population, and co-existing conditions that impair the ability to ingest a large-volume laxative regimen. Improvements in bowel preparation for colonoscopy in hospitalized patients would likely improve patient care and reduce hospital costs. The purpose of this study is to determine if administering a portion of the bowel purgative via EGD could improve colonoscopy preparation in hospitalized patients.
Detailed description
In this randomized controlled trial in hospitalized patients, patients in whom colonoscopy was anticipated the day following EGD were consented and randomized to either standard prep by mouth (split-dose PEG) or intervention group (instillation of the first 2 liters of Nulytely solution through the channel of the endoscope into the duodenal bulb, then continue standard prep). Data is collected on quality of prep and patient satisfaction in both groups.
Interventions
PROCEDUREEGD-assisted administration of colonoscopy prep
Interventional group receive the first 2 liters of prep solution during EGD through the scope channel if colonoscopy expected the following day.
PROCEDUREControl Group received standard prep by oral administration
Control group receive standard oral colonoscopy prep.
Sponsors
Rockford Gastroenterology Associates
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* hospitalized patients * having EGD and expected to have colonoscopy the following day * written informed consent
Exclusion criteria
* unable to tolerate EGD-assisted prep administration
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of bowel preparation | Twenty four to 48 hours - from time of consent prior to EGD until end of colonoscopy performed the following day | Quality of prep was assessed using the Ottawa bowel preparation scale (Rostom A, Jolicoeur E. Validation of a new scale for the assessment of bowel preparation quality. Gastrointest endosc 2004;59:482-6) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient tolerance of bowel preparation | administered just prior to sedation for colonoscopy | Patients in both groups were asked to indicate if the bowel prep was easy, slightly difficult, moderately difficult, extremely difficult, or if they were unable to complete the prep as directed. |
Countries
United States
Outcome results
None listed