Improving the Management of Acute Coronary Syndromes in the Emergency Department

Improving the Management of Acute Coronary Syndromes in the Emergency Department Using a Rapid Acute Cardiac Evaluation Pathway

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01563250

Acronym

RACE

Enrollment

705

Registered

2012-03-26

Start date

2011-06-30

Completion date

2011-12-31

Last updated

2013-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Keywords

Acute Coronary Syndrome, Cardiac Biomarkers, point of care testing

Brief summary

By using a Rapid Cardiac Evaluation (RACE) pathway in the Emergency Department (ED), the investigators can effectively reduce ED wait times and ED length of stay by decreasing overall hospital admissions and telemetry admissions. In addition, the investigators hypothesize a decrease in mortality of those patients admitted for cardiac evaluation by increasing the patient to health care provider ratio.

Interventions

DEVICEPoint of Care testing

The investigators will implement 6 months of randomized testing periods, 2 weeks each. During this 2 week block, cardiac biomarkers will be tested at the bedside in the ED using the Triage Cardiac Panel that will test for CK-MB, Myoglobin, and Troponin I. Each blood sample that is take for point of care testing will be saved. The plasma from the saved sample will be frozen and the sample will be sent to an off-site testing center for high sensitivity troponin testing. All patients will be followed at the 30-day mark and those patients who are discharged home from the ED will be followed within 48 hours as well.

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

35 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Chief complaint of chest pain * 35 years old or greater

Exclusion criteria

* ST elevation MI * New Left Bundle Branch Block * Admission regardless of test result * Leaving ED against medical advice

Design outcomes

Primary

Measure	Time frame	Description
ED length of stay	Average of 3 hours stay in the Emergency Department	From patient check-in time to patient admit or discharge time

Secondary

Measure	Time frame	Description
Mortality rate of admitted patients	During hospital admission and at 30 days	Average hospital stay 3 days.
Hospital Admission Rate	Baseline	Observing the rate at which physicians admit patients to the hospital.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026