Infections, Rotavirus
Conditions
Keywords
Belgium, hospitals, Rotavirus
Brief summary
This study aims to confirm the statistically significant decline in rotavirus related and in acute gastro-enteritis (AGE) related hospital admissions that was observed in 11 participating hospitals, after the introduction of RV vaccines in Belgium in 2006.
Detailed description
This retrospective study will use anonymised data, extracted from hospital databases during the period of the 1st of June 2010 until the 31st of May 2011. IMS Health sales data will be used to provide rotavirus vaccine coverage estimates (Rotarix and Rotateq) for the Belgian population during the study period. Any additional source of vaccine coverage status describing rotavirus vaccine uptake in the study population will also be reported.
Interventions
OTHERData collection
Each participating centre will be requested to generate a coded list of all stool samples taken during the study period (June 1st 2010- May 31st 2011) and analysed for rotavirus, in children aged ≤5 years.
Sponsors
GlaxoSmithKline
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 5 Years
Healthy volunteers
No
Inclusion criteria
* Child aged ≤5 years; * A stool sample has been provided for a rotavirus detection test during the study period; * Laboratory test result of rotavirus is available.
Exclusion criteria
Not applicable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absolute number of rotavirus related hospitalisations in children up to five years old. | During the study period (from June 1st 2010 to May 31st 2011, i.e. up to 1 year) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of rotavirus positive tests on the total number of rota detection tests | During the study period (from June 1st 2010 to May 31st 2011, i.e. up to 1 year) | Total number of rota detection tests and number of rotavirus positive tests of the study year will be determined by age-group of 1-year, gender, time of the event, vaccine coverage status. |
| The duration of rota-related hospitalisation for community acquired and nosocomial infection. | During the study period (from June 1st 2010 to May 31st 2011, i.e. up to 1 year) | — |
Outcome results
None listed