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Glucose as a Mediator of Self-control Performances in Patients With Schizophrenia

Glucose as a Mediator of Self-control Performances in Patients With Schizophrenia: A Randomized Controlled Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01563016
Enrollment
100
Registered
2012-03-26
Start date
2012-04-30
Completion date
2013-04-30
Last updated
2012-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Keywords

schizophrenia, Psychotic Disorders, Psychoses

Brief summary

The research aims to investigate the relationship between self-control ability and blood glucose level in schizophrenic patients. The main purpose of the present study is to explore whether the close relationship of blood glucose and self-regulatory strength observed in healthy individuals, is applicable to schizophrenic patients. More specifically, the current study aims * to investigate whether the exertion of self-control reduces blood glucose, * to examine whether low level of blood glucose deteriorates subsequent self-control performances * to examine whether restoring the glucose level eliminates these impairments, in schizophrenic patients.

Interventions

DIETARY_SUPPLEMENTglucose drink

participants will receive a drink rich in glucose

Sponsors

Queen Mary Hospital, Hong Kong
CollaboratorOTHER
The University of Hong Kong
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Aged 15 or above * DSM-IV diagnosis of schizophrenia, schizoaffective disorder, schizophreniform psychosis, brief psychosis, psychosis NOS or delusional disorder * Cantonese-speaking Chinese * Ability to understand the nature of the study and sign informed consent

Exclusion criteria

* Organic Brain disorder * Known history of intellectual disability * Priority Follow Up (Subtarget or Target) * All allergic to any sugar or artificial sweeteners * Diabetics * Physical Disability

Design outcomes

Primary

MeasureTime frame
Blood Glucose Levelbaseline, after depleting task
self control tasks (handgrip, stroop, figure tracing task)after 12-minutes metabolizing phase

Countries

China

Contacts

Primary ContactEric YH Chen, MD
eyhchen@hku.hk852-22553063
Backup ContactChung-Ming Leung, Bsc
mingming4f29@hotmail.com852-64054460

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026