Gender-specific aEEGs and Outcome in Preterms

Gender-related Differences in Early Amplitude-integrated Electroencephalography in Newborns < 30 Weeks' Gestational Age and Their Correlation With Neurodevelopment Outcome at Three Years Corrected Age

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01562236

Enrollment

148

Registered

2012-03-23

Start date

2000-01-31

Completion date

2011-10-31

Last updated

2012-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gender Role Disorder, Male to Female Type

Brief summary

Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography (aEEG) and to correlate these findings with neurodevelopmental outcome. Methods: Preterm infants born \<30 weeks' gestational age between 2000 and 2002 were prospectively included. aEEGs obtained within the first two weeks of life were evaluated and classified according to background activity, sleep-wake cycling (SWC) and seizure activity. Outcome was assessed at three years.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

24 Weeks to 30 Weeks

Healthy volunteers

Yes

Inclusion criteria

* born\<30 weeks gestational age * who had aEEGs in first 2 weeks of life * who were assessed for outcome at 3 years of age

Exclusion criteria

* born\>30 weeks gestational age * had no aEEGs in first 2 weeks of life * lost for follow-up at 3 years

Countries

Austria

Outcome results