Improving Depression Care for Elders: Coordinating Center

This Was a Five-year Seven-site Trial to Study the Cost-effectiveness of a Population Based Disease Management Program for Late Life Depression in Primary Care.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01561105

Acronym

IMPACT

Enrollment

1801

Registered

2012-03-22

Start date

1999-01-31

Completion date

2004-06-30

Last updated

2012-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depression, Dysthymic Disorder, Both Major Depression and Dysthymic Disorder

Brief summary

Purpose: To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment(IMPACT) collaborative care management program for late-life depression.

Detailed description

This study tested an organized method of delivering care for late life depression in primary care. Specifically, the investigators evaluated the effectiveness of this intervention as compared to 'care as usual'. The investigators studied the effect of the intervention on clinical outcomes such as depressive symptoms, functional status, health related quality of life. They also determined the cost-effectiveness of the intervention compared to care as usual.

Interventions

OTHERIMPACT

IMPACT is a collaborative care management program for late-life depression

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Inclusion criteria

* Major depression or dysthymia as diagnosed by a structured diagnostic interview. * Patient plans to receive primary care at the study clinic for the next year.

Exclusion criteria

* Age under 60. * Current symptoms or history of psychosis or mania as determined by structured diagnostic interview. * Cognitive impairment as defined by a score less than 23 on a Mini Mental Status Examination. * Terminal illness - defined as having a life expectancy of less than 6 months. * Active alcohol abuse as determined by a screening interview. * High suicide risk as determined by current plan for suicide or a history of more than 3 prior suicide attempts in the past 10 years.

Design outcomes

Primary

Measure	Time frame	Description
Severity of depression symptoms	—	Severity measured by the 21-item Hopkins Symptom Checklist.

Secondary

Measure	Time frame	Description
Functioning	—	measured by the Sheehan Health-Related Functioning Index

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 9, 2026