Dietary Vitamin A Requirement in Chinese Children and the New Technology of Dietary Assessment

Estimating Dietary Vitamin A Requirement in Chinese Children by Stable-isotope Dilution Technique

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01559766

Enrollment

403

Registered

2012-03-21

Start date

2009-07-31

Completion date

2010-09-30

Last updated

2012-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin A Deficiency

Keywords

Vitamin A, Dietary requirement, Dietary records, Deuterated retinol dilution technique, Chinese children, Dietary intake of vitamin A, Vitamin A liver reserves

Brief summary

Vitamin A deficiency remains a major public health problem in developing country worldwide. Young Children are considered to be at greatest risk of deficiency. However, there is little information on the vitamin A requirement of Chinese children. In the present study, about 400 children aged between 4 and 9 years old in a kindergarten and an elementary school of Shiyan City were screened before admission by questionnaire and anthropometric measurement. The vitamin A status of children was assessed by serum vitamin A level, relative dosage reaction and stable-isotope dilution technique. At the same time, their dietary vitamin A intakes were estimated by weighted-food dietary survey. The dietary vitamin A requirement in young children was determined on the basis of dietary vitamin A intakes in Children with adequate vitamin A level.

Interventions

None listed

Study design

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

4 Years to 9 Years

Healthy volunteers

Inclusion criteria

* well-nourished children with normal serum retinol(\>=1.40umol/L)

Exclusion criteria

* ongoing or previous illnesses, * having taken nutritional supplements within 3 months, * positive results in the fat absorption test or parasite test, * increased level of CRP (\> 8 mg/L), or * lower serum level of retinol (\< 1.40 umol/L)

Countries

China

Outcome results