Schistosomiasis
Conditions
Keywords
Schistosoma haematobium, schoolchildren, Central Sudan, Praziquantel
Brief summary
The purpose of this study is to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan.
Detailed description
A longitudinal study will be conducted to evaluate the impact of praziquantel for the treatment of Schistosoma haematobium infection among schoolchildren in Al Salamania in Central Sudan. A cohort of schoolchildren (6-15 years of age) was investigated before and 1 year after treatment with a single dose of praziquantel 40mg/kg.
Interventions
DRUGpraziquantel
praziquantel 40 mg/kg oral tablets
Sponsors
Hikma Pharmaceuticals LLC
University of Khartoum
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
6 Years to 15 Years
Healthy volunteers
No
Inclusion criteria
* School children
Exclusion criteria
* Taking praziquantel
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| cure rate | one year | The reduction of the prevalence and intensity of S.haematobium infection following a single dose of praziquantel40mg/kg |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| reduction in the intensity of infection by | one year | will a single dose of PZQ significantly reduced intensity of infection of S. haematobium infection 1 year after treatment |
Countries
Sudan
Outcome results
None listed