Comparison Colon Capsule Endoscopy vs Optical Colonoscopy for Colorectal Cancer Screening in Familiar-Risk Population

Effectiveness of Colon Capsule Endoscopy as Colorectal Cancer Method of Screening in The Familiar-Risk Population

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01557101

Acronym

CRIBADO

Enrollment

200

Registered

2012-03-19

Start date

2012-04-30

Completion date

2013-06-30

Last updated

2014-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer, Genetics of

Brief summary

The purpose of this study is to determine if the adherence to screening in first grade relatives of patients with CCR is higher than optical colonoscopy.

Detailed description

The purpose of this study is to compare the adherence and effectiveness of colon capsule endoscopy (CCE-2) versus conventional colonoscopy to screen first-degree relatives of patients with colorectal cancer.

Interventions

PROCEDURECOLON CAPSULE ENDOSCOPY ADHERENCE

An exploration with a COLON CAPSULE ENDOSCOPY eaten which capsule has a video-camera in both end to see the colon.

PROCEDUREOPTICAL COLONOSCOPY ADHERENCE

An exploration with an OPTICAL COLONOSCOPY from the anus to see the colon.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

40 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Asymptomatic first-degree relatives (parents, siblings or children) of CRC patients aged less than 60 years or with two or more first-degree relatives of any age. * Signing of informed consent.

Exclusion criteria

* Personal history of adenoma or CRC. * History of hereditary CRC. * Chronic inflammatory disease. * Presence of digestive symptoms. * Patients with swallowing problems (dysphagia). * Personal history of gastrointestinal surgery. * Enteritis radioactive. * Renal failure. * Congestive heart failure * Allergy or other contraindication to Bysacodyl to PEG or phosphates. * Pregnancy. * Suspected bowel obstruction or intestinal strictures or fistulas known. * Colectomy. * Paralysis with impaired intestinal motility. * Any other process that the investigator's discretion to make inadequate participation.

Design outcomes

Primary

Measure	Time frame	Description
Participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer	6 month follow up	Assess whether colon capsule endoscopy increases participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 17, 2026