Healthy Subjects
Conditions
Keywords
Mental workload, Multitasking, Protein, Tryptophan
Brief summary
The aim of the study is to investigate the influence of nutritive (high-protein or high-carbohydrate) and non-nutritive (low energy) breakfast on psychological and physiological responses of mental workload during multitasking in healthy volunteers.
Interventions
DIETARY_SUPPLEMENTBreakfast juice
single dose (300 ml) in the morning of study day, 3 separate sessions (high-protein vs. high-carbohydrate vs. low-calorie juice), total duration 3 weeks
Sponsors
Finnish Institute of Occupational Health
SalWe Ltd.
University of Helsinki
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
22 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* eats usually breakfast * use computer mouse with right hand * normal sleep-wake rhythm between 9 pm and 8 am * in females hormonal contraception
Exclusion criteria
* gastrointestinal disease, diabetes or any other significant major medical morbidity * milk allergy * lactose intolerance * smoking * excess use of alcohol, coffee, tea, cola drinks (\> 10 doses/day) * pregnancy and breast feeding * no medication or dietary supplements influencing measured responses * BMI \> 30 kg/m2 or \< 18 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain measures of mental workload (ERP 300 amplitude and latency) and heart rate | 1 day |
Secondary
| Measure | Time frame |
|---|---|
| Blood concentration of tryptophan in relation to other large neutral amino acids | 1 day |
| Subjective mental workload and mood measurement assessed using visual analogue scale in response to test meal. | 1 day |
| cognitive function measurements | 1 day |
| Blood concentration of glucose | 1 day |
| salivary cortisol | 1 day |
Countries
Finland
Outcome results
None listed